Package: MAnorm2
Type: Package
Title: Tools for Normalizing and Comparing ChIP-seq Samples
Version: 1.2.2
Authors@R: person("Shiqi", "Tu", email = "tushiqi@picb.ac.cn",
                  role = c("aut", "cre"),
                  comment = c(ORCID = "0000-0003-3534-5714"))
Description: Chromatin immunoprecipitation followed by high-throughput
        sequencing (ChIP-seq) is the premier technology for profiling
        genome-wide localization of chromatin-binding proteins,
        including transcription factors and histones with various
        modifications. This package provides a robust method for
        normalizing ChIP-seq signals across individual samples or
        groups of samples. It also designs a self-contained system of
        statistical models for calling differential ChIP-seq signals
        between two or more biological conditions as well as for
        calling hypervariable ChIP-seq signals across samples. Refer to
        Tu et al. (2021) <doi:10.1101/gr.262675.120> and Chen et al.
        (2022) <doi:10.1186/s13059-022-02627-9> for associated
        statistical details.
URL: https://github.com/tushiqi/MAnorm2
BugReports: https://github.com/tushiqi/MAnorm2/issues
License: GPL-3
Encoding: UTF-8
LazyData: true
Depends: R (>= 3.5.0)
Imports: stats, graphics, methods, locfit (>= 1.5.9), scales (>=
        0.3.0), statmod (>= 1.4.34)
Suggests: gplots (>= 3.0.1), DescTools (>= 0.99.24), knitr, rmarkdown
Date: 2022-10-28
RoxygenNote: 7.1.1
VignetteBuilder: knitr
Repository: https://tushiqi.r-universe.dev
Date/Publication: 2022-11-03 07:35:04 UTC
RemoteUrl: https://github.com/tushiqi/manorm2
RemoteRef: HEAD
RemoteSha: 5fd6bdb1a19f5f4cd000a9ed4c804dcddcc443b5
NeedsCompilation: no
Packaged: 2026-10-05 08:45:24 UTC; root
Author: Shiqi Tu [aut, cre] (ORCID: <https://orcid.org/0000-0003-3534-5714>)
Maintainer: Shiqi Tu <tushiqi@picb.ac.cn>